
Plena Health
The AI Operating System for Specialty Medical Practices.
🇺🇸 San Francisco · Healthcare · Spring 2026
Plena is the AI operating system for specialty medical practices
Backed by
Y Combinator
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About Plena Health
Plena is the integrated AI operating system for specialty medical practices. We automate the back-office work that keeps clinics running — referrals, fax intake, scheduling, prior auths, billing — everything that isn't the medicine. We don't replace the EMR or ask staff to learn a new system. We live inside the tools practices already use (EHRs, fax, phones, clearinghouses, payer portals, patient communication) and quietly take over the rote work end-to-end. A Palantir-like base platform of reusable building blocks lets us stand up a custom deployment for each practice in days, not quarters.
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